Pub. Date : 2014 May
PMID : 24480460
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of cells overexpressing Aurora-A and ATM/Chk2 with the ATM specific inhibitor KU-55933 increased the cell sensitivity to cisplatin and irradiation through increasing the phosphorylation of p53 at Ser15 and inhibiting the expression of Chk2, gammaH2AX (Ser319), and RAD51. | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | ATM serine/threonine kinase | Homo sapiens |
| 2 | Treatment of cells overexpressing Aurora-A and ATM/Chk2 with the ATM specific inhibitor KU-55933 increased the cell sensitivity to cisplatin and irradiation through increasing the phosphorylation of p53 at Ser15 and inhibiting the expression of Chk2, gammaH2AX (Ser319), and RAD51. | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | ATM serine/threonine kinase | Homo sapiens |