Title : Placental CYP27B1 and CYP24A1 expression in human placental tissue and their association with maternal and neonatal calcitropic hormones.

Pub. Date : 2014 Apr

PMID : 24471562






2 Functional Relationships(s)
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1 MAIN OUTCOMES: Protein and mRNA expressions of CYP27B1, CYP24A1, and vitamin D receptor were measured in term placental tissue and related to 25-hydroxyvitamin D [25(OH)D], 1,25-dihydroxyvitamin D, PTH, serum total calcium, IL-6, leptin, and osteoprotegerin measured in maternal serum at midgestation and delivery and in umbilical cord serum at birth. 1,25-dihydroxyvitamin D cytochrome P450 family 27 subfamily B member 1 Homo sapiens
2 Maternal serum 1,25-dihydroxyvitamin D concentrations at midgestation were positively correlated with term placental CYP27B1 mRNA expression (n = 49, P = .002). 1,25-dihydroxyvitamin D cytochrome P450 family 27 subfamily B member 1 Homo sapiens