Title : Proteolysis of human alpha 2-macroglobulin without hydrolysis of the internal thiolesters or expression of the receptor recognition site.

Pub. Date : 1988 Jan 5

PMID : 2447076






1 Functional Relationships(s)
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1 The major observations are that despite extensive proteolysis, alpha 2M largely retained its native conformation as shown by rate electrophoresis, the absence of binding of monoclonal antibody F2B2, and the incorporation of [14C]methylamine into a 145-kDa fragment of alpha 2M. Carbon-14 alpha-2-macroglobulin Homo sapiens