Title : New chemical scaffolds for human african trypanosomiasis lead discovery from a screen of tyrosine kinase inhibitor drugs.

Pub. Date : 2014

PMID : 24468788






2 Functional Relationships(s)
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1 Lapatinib, CI-1033, erlotinib, axitinib, sunitinib, PKI-166, and AEE788 inhibited the replication of bloodstream T. brucei, with a 50% growth inhibitory concentration (GI50) between 1.3 muM and 2.5 muM. Lapatinib latexin Homo sapiens
2 Lapatinib, CI-1033, erlotinib, axitinib, sunitinib, PKI-166, and AEE788 inhibited the replication of bloodstream T. brucei, with a 50% growth inhibitory concentration (GI50) between 1.3 muM and 2.5 muM. Lapatinib latexin Homo sapiens