Title : Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells.

Pub. Date : 2014

PMID : 24466341






3 Functional Relationships(s)
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1 DHT-induced AR transactivation was coupled with higher nuclear translocation of p65-Nrf1 in C4-2B cells, as compared to LNCaP cells. Dihydrotestosterone nuclear respiratory factor 1 Homo sapiens
2 Our findings also indicate that the DHT-stimulated increase in p65-Nrf1 and the simultaneous suppression of both Nrf2 and p120-Nrf1 ultimately facilitates AR transactivation in CRPC cells. Dihydrotestosterone nuclear respiratory factor 1 Homo sapiens
3 Our findings also indicate that the DHT-stimulated increase in p65-Nrf1 and the simultaneous suppression of both Nrf2 and p120-Nrf1 ultimately facilitates AR transactivation in CRPC cells. Dihydrotestosterone nuclear respiratory factor 1 Homo sapiens