Title : Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition.

Pub. Date : 2014 Apr

PMID : 24459178






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In an in vivo study, an increased distribution of edoxaban to the brain was observed in Mdr1a/1b knockout mice when compared with wild-type mice, indicating that edoxaban is a substrate for P-gp. edoxaban phosphoglycolate phosphatase Mus musculus
2 In an in vivo study, an increased distribution of edoxaban to the brain was observed in Mdr1a/1b knockout mice when compared with wild-type mice, indicating that edoxaban is a substrate for P-gp. edoxaban phosphoglycolate phosphatase Mus musculus