Title : Elevated cAMP increases aquaporin-3 plasma membrane diffusion.

Pub. Date : 2014 Mar 15

PMID : 24452376






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 The reabsorped water exits via basolateral AQP3 and AQP4. Water aquaporin 3 (Gill blood group) Homo sapiens
2 To facilitate the increase in transepithelial water transport, AQP3 may be short-term regulated via changes in protein-protein interactions, incorporation into lipid rafts, and/or changes in steady-state turnover, which could result in changes in the diffusion behavior of AQP3. Water aquaporin 3 (Gill blood group) Homo sapiens
3 Thus AQP3-EGFP diffusion is altered upon increased cAMP, which may correspond to basolateral adaptations in response to the increased apical water readsorption. Water aquaporin 3 (Gill blood group) Homo sapiens