Title : Phase I dosage finding and pharmacokinetic study of intravenous topotecan and oral erlotinib in adults with refractory solid tumors.

Pub. Date : 2014 Mar

PMID : 24448640






2 Functional Relationships(s)
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1 PURPOSE: Topotecan is widely used for refractory solid tumors but multi-drug resistance may occur due to tumor expression of ATP-binding cassette (ABC) transporters. Topotecan ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens
2 PURPOSE: Topotecan is widely used for refractory solid tumors but multi-drug resistance may occur due to tumor expression of ATP-binding cassette (ABC) transporters. Topotecan ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens