Title : Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy.

Pub. Date : 2014 May 5

PMID : 24402559






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LTA responses to TRAP and CAT and VerifyNow results were markedly inhibited by vorapaxar. vorapaxar TRAP Homo sapiens
2 Maximal LTA response to TRAP (median, interquartile range) 2 hours post loading dose: placebo 68% (53-75%) and vorapaxar 3% (2-6%), p<0.0001. vorapaxar TRAP Homo sapiens