Pub. Date : 2014 May
PMID : 24399651
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The impact of arsenic trioxide and all-trans retinoic acid on p53 R273H-codon mutant glioblastoma. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 2 | The results showed that U87-p53(R273H) cells generated more rapid neurosphere growth than U87-p53(wt) but inhibition of neurosphere proliferation was seen with both ATO and ATRA. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 3 | U87-p53(R273H) neurospheres showed resistance to differentiation into glial cells and neuronal cells with ATO and ATRA exposure. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 4 | ATO was able to generate apoptosis at high doses and proliferation of U87-p53(wt) and U87-p53(R273H) cells was reduced with ATO and ATRA in a dose-dependent manner. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 5 | ATO was able to generate apoptosis at high doses and proliferation of U87-p53(wt) and U87-p53(R273H) cells was reduced with ATO and ATRA in a dose-dependent manner. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 6 | ATO was able to generate apoptosis at high doses and proliferation of U87-p53(wt) and U87-p53(R273H) cells was reduced with ATO and ATRA in a dose-dependent manner. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 7 | ATO was able to generate apoptosis at high doses and proliferation of U87-p53(wt) and U87-p53(R273H) cells was reduced with ATO and ATRA in a dose-dependent manner. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 8 | Elevated pERK1/2 and p53 expression was seen in U87-p53(R273H) neurospheres, which could be reduced with ATO and ATRA treatment. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 9 | Elevated pERK1/2 and p53 expression was seen in U87-p53(R273H) neurospheres, which could be reduced with ATO and ATRA treatment. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |