Title : Effect of vitamin D supplementation on cathelicidin, IFN-γ, IL-4 and Th1/Th2 transcription factors in young healthy females.

Pub. Date : 2014 Mar

PMID : 24398649






2 Functional Relationships(s)
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1 OBJECTIVES: We assessed the effect of cholecalciferol and calcium supplementation on mRNA expression of cathelicidin (LL-37), Th1 and Th2 cytokines and their transcription factors in the peripheral blood mononuclear cells (PBMCs) in healthy females with vitamin D deficiency (VDD). Cholecalciferol cathelicidin antimicrobial peptide Homo sapiens
2 Despite significant increase in mean serum 25(OH)D in the cholecalciferol-supplemented groups, their mean mRNA transcripts of LL-37, IFN-gamma, IL-4, transcription factors and their IFN-gamma/IL-4 and T-bet/GATA-3 ratios were similar to that of calcium and placebo groups. Cholecalciferol cathelicidin antimicrobial peptide Homo sapiens