Title : Post-transcriptional repression of FOXO1 by QKI results in low levels of FOXO1 expression in breast cancer cells.

Pub. Date : 2014 Mar

PMID : 24398626






2 Functional Relationships(s)
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Protein Name
Organism
1 ATRA, an inducer of apoptosis or differentiation, dramatically enhanced FOXO1 expression while it repressed QKI expression. Tretinoin QKI, KH domain containing RNA binding Homo sapiens
2 Importantly, the ATRA-induced increase in FOXO1 expression was dependent on QKI-mediated post-transcriptional regulation. Tretinoin QKI, KH domain containing RNA binding Homo sapiens