Title : Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1.

Pub. Date : 2014 Mar

PMID : 24396067






1 Functional Relationships(s)
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1 We also showed that CTLA-4 receptor signaling mediates tyrosine phosphorylation in the C3G protein, and that this is required for augmented activation of Rap1 and increased adhesion mediated by leukocyte function-associated antigen type 1 (LFA-1). Tyrosine Rap guanine nucleotide exchange factor 1 Homo sapiens