Title : Hepatotoxicity in rats treated with dimethylformamide or toluene or both.

Pub. Date : 2013 Sep

PMID : 24386519






3 Functional Relationships(s)
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1 The immunoblots indicated that the expression of CYP2E1 was considerably enhanced depending on the dosage of DMF and the CYP2E1 blot densities were significantly increased after treatment with both DMF and toluene, compared to treatment with DMF alone. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
2 The immunoblots indicated that the expression of CYP2E1 was considerably enhanced depending on the dosage of DMF and the CYP2E1 blot densities were significantly increased after treatment with both DMF and toluene, compared to treatment with DMF alone. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
3 These results suggest that the expression of CYP2E1 is induced by DMF and enhanced by toluene. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus