Title : Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects.

Pub. Date : 2013 Oct

PMID : 24379961






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1 MATERIALS AND METHODS: In the current study, based on the potential inhibitory activity of phthalimide derivatives towards acetylcholinesterase enzyme, a new series of phthalimide-based compounds were synthesized (4a-4e) and anti-acetylcholinesterase effect was assessed using Ellman"s test. phthalimide acetylcholinesterase (Cartwright blood group) Homo sapiens
2 MATERIALS AND METHODS: In the current study, based on the potential inhibitory activity of phthalimide derivatives towards acetylcholinesterase enzyme, a new series of phthalimide-based compounds were synthesized (4a-4e) and anti-acetylcholinesterase effect was assessed using Ellman"s test. phthalimide acetylcholinesterase (Cartwright blood group) Homo sapiens
3 MATERIALS AND METHODS: In the current study, based on the potential inhibitory activity of phthalimide derivatives towards acetylcholinesterase enzyme, a new series of phthalimide-based compounds were synthesized (4a-4e) and anti-acetylcholinesterase effect was assessed using Ellman"s test. phthalimide acetylcholinesterase (Cartwright blood group) Homo sapiens
4 MATERIALS AND METHODS: In the current study, based on the potential inhibitory activity of phthalimide derivatives towards acetylcholinesterase enzyme, a new series of phthalimide-based compounds were synthesized (4a-4e) and anti-acetylcholinesterase effect was assessed using Ellman"s test. phthalimide acetylcholinesterase (Cartwright blood group) Homo sapiens
5 CONCLUSION: The new synthesized phthalimide based analogs could function as potential acetylcholinesterase inhibitors. phthalimide acetylcholinesterase (Cartwright blood group) Homo sapiens