Title : Celecoxib potentially inhibits metastasis of lung cancer promoted by surgery in mice, via suppression of the PGE2-modulated β-catenin pathway.

Pub. Date : 2014 Mar 3

PMID : 24374173






2 Functional Relationships(s)
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Protein Name
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1 The expression of protein and mRNA of MMP9 and E-cadherin following treatment with PGE2 were suppressed and increased by celecoxib, respectively; however, MMP2 showed no change. Celecoxib cadherin 1 Mus musculus
2 Deletion of beta-catenin by siRNA abrogated celecoxib-induced inhibition of MMP9 up-regulation and E-cadherin down-regulation by treatment of PGE2. Celecoxib cadherin 1 Mus musculus