Title : Rho-kinase limits BMP-4-stimulated osteocalcin synthesis in osteoblasts: regulation of the p38 MAP kinase pathway.

Pub. Date : 2014 Feb 6

PMID : 24368139






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Y27632 or fasudil, specific inhibitors of Rho-kinase, which attenuated the MYPT-1 phosphorylation, significantly amplified the BMP-4-stimulated osteocalcin synthesis in a dose-dependent manner. Y 27632 Rho-associated coiled-coil containing protein kinase 2 Mus musculus