Title : Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling.

Pub. Date : 2014 Feb 7

PMID : 24366863






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Asparagine deamidation occurs spontaneously in proteins during aging; deamidation of Asn-Gly-Arg (NGR) sites can lead to the formation of isoAsp-Gly-Arg (isoDGR), a motif that can recognize the RGD-binding site of integrins. Asparagine reticulon 4 receptor Homo sapiens
2 We observed that the exposed (568)NGR site can deamidate under conditions mimicking accelerated Asn aging. Asparagine reticulon 4 receptor Homo sapiens