Title : Antigenic heterogeneity of carcinoembryonic antigen in the circulation defined by monoclonal antibodies against the carbohydrate moiety of carcinoembryonic antigen and closely related antigens.

Pub. Date : 1987 Jan 1

PMID : 2431767






5 Functional Relationships(s)
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1 Antigenic heterogeneity of carcinoembryonic antigen in the circulation defined by monoclonal antibodies against the carbohydrate moiety of carcinoembryonic antigen and closely related antigens. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens
2 Antigenic heterogeneity of carcinoembryonic antigen in the circulation defined by monoclonal antibodies against the carbohydrate moiety of carcinoembryonic antigen and closely related antigens. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens
3 The serum CEA values estimated with these four antibodies were highly variable depending on the antibody used, suggesting that the expression of carbohydrate epitopes on the CEA molecules in patient sera was quite heterogeneous. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens
4 The serum CEA values estimated with these four antibodies were highly variable depending on the antibody used, suggesting that the expression of carbohydrate epitopes on the CEA molecules in patient sera was quite heterogeneous. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens
5 The results obtained suggest that, at least in part, the diversity of antigenic expression on carbohydrate chains on the CEA molecules in patient sera and the variation in specificity or quantity of anti-carbohydrate antibodies in the polyclonal antibody preparations used for the respective assay systems may result in the differences in the estimated CEA values. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens