Title : Structure of the β-form of human MK2 in complex with the non-selective kinase inhibitor TEI-L03090.

Pub. Date : 2013 Dec

PMID : 24316826






2 Functional Relationships(s)
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1 In a previous report, it was shown that MK2 in complex with the selective inhibitor TEI-I01800 adopts an alpha-helical glycine-rich loop that is induced by the stable nonplanar conformer of TEI-I01800. Glycine MAPK activated protein kinase 2 Homo sapiens
2 MK2-TEI-L03090 has a beta-sheet glycine-rich loop in common with other kinases, as predicted. Glycine MAPK activated protein kinase 2 Homo sapiens