Pub. Date : 2014 Aug
PMID : 24311107
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previous studies have shown that some polymorphisms of the gene encoding farnesyl diphosphate synthase (FDPS), the main target of aminobisphosphonates, modulate the response to these drugs. | aminobisphosphonates | farnesyl diphosphate synthase | Homo sapiens |
| 2 | Previous studies have shown that some polymorphisms of the gene encoding farnesyl diphosphate synthase (FDPS), the main target of aminobisphosphonates, modulate the response to these drugs. | aminobisphosphonates | farnesyl diphosphate synthase | Homo sapiens |
| 3 | In conclusion, these results suggest that polymorphisms of the FDPS gene may influence the bone response to various drugs targeting the mevalonate pathway, including not only aminobisphosphonates but also statins. | aminobisphosphonates | farnesyl diphosphate synthase | Homo sapiens |