Title : Hemin/G-quadruplex-catalyzed aerobic oxidation of thiols to disulfides: application of the process for the development of sensors and aptasensors and for probing acetylcholine esterase activity.

Pub. Date : 2013 Dec 17

PMID : 24299064






2 Functional Relationships(s)
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Protein Name
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1 The AChE-catalyzed hydrolysis of acetylthiocholine to the thiol-functionalized thiocholine enabled the probing of the enzymatic activity of AChE through the hemin/G-quadruplex-catalyzed aerobic oxidation of thiocholine to the respective disulfide and the concomitant generation of the fluorescent resorufin product. Sulfhydryl Compounds acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The AChE-catalyzed hydrolysis of acetylthiocholine to the thiol-functionalized thiocholine enabled the probing of the enzymatic activity of AChE through the hemin/G-quadruplex-catalyzed aerobic oxidation of thiocholine to the respective disulfide and the concomitant generation of the fluorescent resorufin product. Sulfhydryl Compounds acetylcholinesterase (Cartwright blood group) Homo sapiens