Title : Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase.

Pub. Date : 2014 Jan 5

PMID : 24298159






1 Functional Relationships(s)
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1 NGL-3 cleavage is induced by NMDA treatment in cultured neurons and low-frequency stimulation in brain slices and requires the activities of NMDA glutamate receptors, matrix metalloproteinases (MMPs) and presenilin/gamma-secretase. N-Methylaspartate leucine rich repeat containing 4B Homo sapiens