Title : Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer.

Pub. Date : 2014 Feb 15

PMID : 24284055






1 Functional Relationships(s)
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1 EXPERIMENTAL DESIGN: SCLC models of HGF-induced EMT were evaluated in vitro and in vivo (subcutaneous xenografts in BALB/c nude mice) for chemosensitivity and response to Met inhibition with PF-2341066 (crizotinib). Crizotinib hepatocyte growth factor Mus musculus