Title : Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction.

Pub. Date : 2014 Jan 15

PMID : 24282278






2 Functional Relationships(s)
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1 Moreover, His-MDA-7, after binding to its cognate receptors (IL-20R1/IL-20R2 or IL-22R/IL-20R2), induces intracellular signaling by phosphorylation of p38 MAPK, leading to transcription of a family of growth arrest and DNA damage inducible (GADD) genes, culminating in apoptosis. gadd interleukin 20 receptor subunit beta Homo sapiens
2 Moreover, His-MDA-7, after binding to its cognate receptors (IL-20R1/IL-20R2 or IL-22R/IL-20R2), induces intracellular signaling by phosphorylation of p38 MAPK, leading to transcription of a family of growth arrest and DNA damage inducible (GADD) genes, culminating in apoptosis. gadd interleukin 20 receptor subunit beta Homo sapiens