Title : Activation of NAD(P)H oxidase by tryptophan-derived 3-hydroxykynurenine accelerates endothelial apoptosis and dysfunction in vivo.

Pub. Date : 2014 Jan 31

PMID : 24281189






1 Functional Relationships(s)
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1 Furthermore, interferon-gamma neutralization eliminates AngII-increased superoxide products and endothelial apoptosis by inhibiting AngII-induced Kynurenines generation, suggesting that AngII-activated Kyn pathway is interferon-gamma-dependent. Superoxides interferon gamma Mus musculus