Title : Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.

Pub. Date : 2014 Apr 15

PMID : 24271013






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fenofibrate and gemfibrozil, previously reported to induce TPP1 activity in control cells, failed to increase TPP1 activity in patient iPSC-derived neural progenitor cells. Gemfibrozil tripeptidyl peptidase 1 Homo sapiens