Title : Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents.

Pub. Date : 2014 Jan 1

PMID : 24268795






1 Functional Relationships(s)
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1 Seven compounds showed an antiproliferative profile superior to the p53-MDM2 interaction inhibitor nutlin-3, and induced cell death by apoptosis. nutlin 3 tumor protein p53 Homo sapiens