Title : Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome).

Pub. Date : 2014 May

PMID : 24266877






1 Functional Relationships(s)
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1 The results of the present study support the existing evidence that the CUL3 and KLHL3 gene products are physiologically important regulators of thiazide-sensitive distal nephron NaCl reabsorption, and hence potentially interesting novel anti-hypertensive drug targets. Thiazides kelch like family member 3 Homo sapiens