Title : Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination.

Pub. Date : 2013 Dec 27

PMID : 24247240






1 Functional Relationships(s)
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1 Here, we show that H-Ras is activated by monoubiquitination and that ubiquitination at Lys-117 accelerates intrinsic nucleotide exchange, thereby promoting GTP loading. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens