Title : Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors.

Pub. Date : 2013

PMID : 24244317






1 Functional Relationships(s)
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1 Conformationally constrained phenethylamine analogs have demonstrated that for optimal activity the free lone pair electrons of the 2-oxygen must be oriented syn and the 5-oxygen lone pairs anti relative to the ethylamine moiety. Oxygen synemin Homo sapiens