Title : Continuous-flow fast atom bombardment mass spectrometry of oligonucleotides.

Pub. Date : 1991 Apr

PMID : 24242175






4 Functional Relationships(s)
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1 Mobilephase composition, flow rate, and sample size were optimized for the analysis of oligonucleotides by negative ion frit-FAB mass spectrometry (a type of continuous-flow FAB mass spectrometry). Oligonucleotides FA complementation group B Homo sapiens
2 Equimolar mixtures of two or three oligonucleotides produced deprotonated molecules in identical relative abundances whether analyzed by frit-FAB or standard probe FAB mass spectrometry. Oligonucleotides FA complementation group B Homo sapiens
3 Equimolar mixtures of two or three oligonucleotides produced deprotonated molecules in identical relative abundances whether analyzed by frit-FAB or standard probe FAB mass spectrometry. Oligonucleotides FA complementation group B Homo sapiens
4 Finally, frit-FAB liquid chromatography mass spectrometry was demonstrated by separating mixtures of oligonucleotides on a beta -cyclodextrin high-performance liquid chromatography column with a mobile phase containing methanol, water, and triethanolamine. Oligonucleotides FA complementation group B Homo sapiens