Title : Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity.

Pub. Date : 2014 Apr

PMID : 24241710






1 Functional Relationships(s)
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1 Recent genetic evidence suggests that the diacylglycerol lipase (DAGL-alpha) isoform is the major biosynthetic enzyme for the most abundant endocannabinoid, 2-arachidonoyl-glycerol (2-AG), in the central nervous system. Endocannabinoids diacylglycerol lipase alpha Homo sapiens