Title : The effect of the skeleton structure of flavanone and flavonoid on interaction with transferrin.

Pub. Date : 2013 Dec 15

PMID : 24239187






6 Functional Relationships(s)
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1 Our results demonstrated that naringenin bound transferrin with an affinity almost 100 times higher than that of apigenin attributed to its higher structural flexibility and lower acidity compared with apigenin. naringenin transferrin Homo sapiens
2 Our docking study showed that naringenin had stronger van der Waals interactions with transferrin, which was believed to contribute to its higher binding affinity. naringenin transferrin Homo sapiens
3 We also found that naringenin-binding induced greater increase in the alpha-helix content in transferrin than apigenin, suggesting that transferrin became more compact upon association with naringenin. naringenin transferrin Homo sapiens
4 We also found that naringenin-binding induced greater increase in the alpha-helix content in transferrin than apigenin, suggesting that transferrin became more compact upon association with naringenin. naringenin transferrin Homo sapiens
5 We also found that naringenin-binding induced greater increase in the alpha-helix content in transferrin than apigenin, suggesting that transferrin became more compact upon association with naringenin. naringenin transferrin Homo sapiens
6 Our study demonstrated that naringenin was a ligand for transferrin with good affinity. naringenin transferrin Homo sapiens