Pub. Date : 2013 Jul
PMID : 24228511
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | [Effect of the methylation enzyme inhibitors of 5-aza-2-deoxycytidine on the TGF-beta/smad signal transduction pathway in human keloid fibroblasts]. | Decitabine | transforming growth factor beta 1 | Homo sapiens |
2 | OBJECTIVE: To investigate the effect of 5-aza-2-deoxycytidine on the TGF-beta/smad signal transduction pathway in human keloid fibroblasts (KFSs). | Decitabine | transforming growth factor beta 1 | Homo sapiens |
3 | CONCLUSIONS: 5-aza-2-deoxycytidine, methylase inhibitors, inhibits cell proliferation and promotes apoptosis of KFSs, which may be associated with the suppression of TGF-beta/smad signal pathway. | Decitabine | transforming growth factor beta 1 | Homo sapiens |