Pub. Date : 2013
PMID : 24223706
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells. | dihydromyricetin | tumor protein p53 | Homo sapiens |
| 2 | In this study, we investigated whether p53 is involved in DHM-triggered viability inhibition and apoptosis induction in cancer cells. | dihydromyricetin | tumor protein p53 | Homo sapiens |
| 3 | P53 expression was significantly increased after DHM treatment, whereas Bcl-2 was reduced potently. | dihydromyricetin | tumor protein p53 | Homo sapiens |
| 4 | These findings defined and supported a novel function that DHM could induce human hepatocellular carcinoma HepG2 cells apoptosis by up-regulating Bax/Bcl-2 expression via p53 signal pathway. | dihydromyricetin | tumor protein p53 | Homo sapiens |