Title : MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer.

Pub. Date : 2013 Dec 11

PMID : 24211253






1 Functional Relationships(s)
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1 Mechanistically, inhibition of MEK1 by both PD98059 and U0126 as well as RNAi reduces beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC), which acts as a potential endogenous YAP protector. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase kinase 1 Homo sapiens