Pub. Date : 2013 Dec
PMID : 24211095
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenic trioxide induces apoptosis in B-cell chronic lymphocytic leukemic cells through down-regulation of survivin via the p53-dependent signaling pathway. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 2 | WSU-CLL cells treated with 2muM As2O3 showed survivin down-regulation and p53 up-regulation. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 3 | p53 inhibition by siRNA prevented the down-regulation of survivin by As2O3 and prevented the As2O3-induced cytotoxicity of WSU-CLL cells. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
| 4 | p53 inhibition by siRNA prevented the down-regulation of survivin by As2O3 and prevented the As2O3-induced cytotoxicity of WSU-CLL cells. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |