Pub. Date : 2013 Dec
PMID : 24201082
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nicotine injection in full-thickness excisional skin wounds minimally affected inflammatory mediators like TNF, IL-6 and IL-12 while it induced a down-regulation in the expression of growth factors like VEGF, PDGF, TGF-beta1 and TGF-beta2, and the anti-inflammatory cytokine IL-10. | Nicotine | vascular endothelial growth factor A | Mus musculus |
2 | Moreover, nicotine was shown to down-regulate VEGF, PDGF and TGF-beta1 in both bone marrow derived macrophages and RAW 264.7 cells. | Nicotine | vascular endothelial growth factor A | Mus musculus |