Title : Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid.

Pub. Date : 2014 Mar

PMID : 24197982






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In our present study, we found in apoptotic gastric cancer BGC-823 cells induced by ursolic acid that a translocation of cofilin-1 protein from the cytoplasm to the mitochondria promoted the release of cytochrome c from the mitochondria to the cytoplasm, thereby activating the caspase cascade and finally inducing gastric cancer cell apoptosis. ursolic acid cytochrome c, somatic Homo sapiens