Title : EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.

Pub. Date : 2014 Apr

PMID : 24176719






5 Functional Relationships(s)
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1 EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis. Glycosaminoglycans exostosin-like glycosyltransferase 2 Mus musculus
2 Taken together, these results indicated that the EXTL2-dependent mechanism that regulates GAG biosynthesis is important for the maintenance of tissue homeostasis under pathological conditions, that is, lack of EXTL2 causes GAG overproduction and structural changes of GAGs associated with pathological processes. Glycosaminoglycans exostosin-like glycosyltransferase 2 Mus musculus
3 Taken together, these results indicated that the EXTL2-dependent mechanism that regulates GAG biosynthesis is important for the maintenance of tissue homeostasis under pathological conditions, that is, lack of EXTL2 causes GAG overproduction and structural changes of GAGs associated with pathological processes. Glycosaminoglycans exostosin-like glycosyltransferase 2 Mus musculus
4 Taken together, these results indicated that the EXTL2-dependent mechanism that regulates GAG biosynthesis is important for the maintenance of tissue homeostasis under pathological conditions, that is, lack of EXTL2 causes GAG overproduction and structural changes of GAGs associated with pathological processes. Glycosaminoglycans exostosin-like glycosyltransferase 2 Mus musculus
5 Taken together, these results indicated that the EXTL2-dependent mechanism that regulates GAG biosynthesis is important for the maintenance of tissue homeostasis under pathological conditions, that is, lack of EXTL2 causes GAG overproduction and structural changes of GAGs associated with pathological processes. Glycosaminoglycans exostosin-like glycosyltransferase 2 Mus musculus