Pub. Date : 2014 Jan
PMID : 24170769
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sorafenib suppresses JNK-dependent apoptosis through inhibition of ZAK. | Sorafenib | mitogen-activated protein kinase kinase kinase 20 | Homo sapiens |
| 2 | Here, we report that sorafenib suppresses UV-induced apoptosis specifically by inhibiting c-jun-NH(2)-kinase (JNK) activation through the off-target inhibition of leucine zipper and sterile alpha motif-containing kinase (ZAK). | Sorafenib | mitogen-activated protein kinase kinase kinase 20 | Homo sapiens |