Title : Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.

Pub. Date : 2013 Dec 6

PMID : 24142790






1 Functional Relationships(s)
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1 Inhibition of PCYT2 by meclizine led to rapid accumulation of its substrate, phosphoethanolamine, which is itself an inhibitor of mitochondrial respiration. phosphorylethanolamine phosphate cytidylyltransferase 2, ethanolamine Homo sapiens