Pub. Date : 2013 Nov
PMID : 24142642
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Influence of methylenetetrahydrofolate reductase C677T polymorphism on the risk of lung cancer and the clinical response to platinum-based chemotherapy for advanced non-small cell lung cancer: an updated meta-analysis. | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |
2 | PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) has been implicated in lung cancer risk and response to platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |
3 | PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) has been implicated in lung cancer risk and response to platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |
4 | We performed meta-analysis to investigate the effect of MTHFR C677T polymorphism on lung cancer risk and response to platinum-based chemotherapy in advanced NSCLC. | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |
5 | In addition, MTHFR 677TT homozygote carriers had a better response to platinum-based chemotherapy in advanced NSCLC in the recessive model. | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |
6 | CONCLUSION: The MTHFR C677T polymorphism might be a genetic marker for lung cancer risk or response to platinum- based chemotherapy in advanced NSCLC. | Platinum | methylenetetrahydrofolate reductase | Homo sapiens |