Title : Two fluorogenic substrates for purine nucleoside phosphorylase, selective for mammalian and bacterial forms of the enzyme.

Pub. Date : 2014 Feb 1

PMID : 24140360






1 Functional Relationships(s)
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1 Two nontypical nucleosides, 7-beta-D-ribosyl-2,6-diamino-8-azapurine and 8-beta-D-ribosyl-2,6-diamino-8-azapurine, have been found to exhibit moderately good, and selective, substrate properties toward calf and bacterial (Escherichia coli) forms of purine nucleoside phosphorylase (PNP). Nucleosides purine nucleoside phosphorylase Homo sapiens