Pub. Date : 2013 Dec 15
PMID : 24126416
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silencing of Hsp27 and Hsp72 in glioma cells as a tool for programmed cell death induction upon temozolomide and quercetin treatment. | Quercetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 2 | The aim of the present study was to investigate whether silencing of Hsp27 or Hsp72 expression in glioblastoma multiforme T98G and anaplastic astrocytoma MOGGCCM cells increases their sensitivity to programmed cell death induction upon temozolomide and/or quercetin treatment. | Quercetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 3 | Our results indicate that blocking of Hsp27 and Hsp72 expression makes T98G cells and MOGGCCM cells extremely vulnerable to apoptosis induction upon temozolomide and quercetin treatment and that programmed cell death is initiated by an internal signal. | Quercetin | heat shock protein family B (small) member 1 | Homo sapiens |