Pub. Date : 2014 Feb
PMID : 24123616
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Physiological oxygen prevents frequent silencing of the DLK1-DIO3 cluster during human embryonic stem cells culture. | Oxygen | delta like non-canonical Notch ligand 1 | Homo sapiens |
| 2 | Furthermore, we demonstrated that 5% oxygen, instead of the commonly used 20% oxygen, is required for preserving the expression of the DLK1-DIO3 cluster. | Oxygen | delta like non-canonical Notch ligand 1 | Homo sapiens |
| 3 | Overall, the data suggest that active expression of the DLK1-DIO3 cluster represents a new biomarker for epigenetic stability of hESCs and indicates the importance of using a proper physiological oxygen level during the derivation and culture of hESCs. | Oxygen | delta like non-canonical Notch ligand 1 | Homo sapiens |