Title : Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation.

Pub. Date : 2014 Jan

PMID : 24120649






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, we show that ganglioside GM3 inhibits the VEGF-induced expression of intracellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) through activation of nuclear factor-kappaB (NF-kappaB) via protein kinase B (AKT) signaling in human umbilical vein endothelial cells (HUVECs), relating with leukocyte recruitment to endothelial cells under inflammatory conditions. Gangliosides granulocyte macrophage antigen 3 Mus musculus