Title : Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia-reperfusion injury.

Pub. Date : 2013 Nov

PMID : 24117266






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results showed that FGF-21 treatment prevented the oxidative stress and apoptosis associated with I/R damage by reducing the levels of superoxide anions, inhibiting glycogen synthase kinase (GSK) 3beta by activating Akt phosphorylation, and recovering the levels of ATP synthase pyruvate kinase isozymes M1 and protein kinase C, thereby improving energy supply. Superoxides fibroblast growth factor 21 Rattus norvegicus