Title : Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.

Pub. Date : 2014 Jan 1

PMID : 24104877






1 Functional Relationships(s)
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1 DGT-dependent ROS was suppressed by the inhibition of PI3K, PKC, and the mitochondrial KATP channel, suggesting roles for these proteins, respectively, in activation of NOX2 and in mitochondrial ROS generation. Digitoxin cytochrome b-245, beta polypeptide Mus musculus